The essentials at a glance

HBV causes acute or chronic inflammation of the liver. Chronic infection requires monitoring even without symptoms.

What is it?

HBV causes acute or chronic inflammation of the liver. Chronic infection requires monitoring even without symptoms.

How is it transmitted?

Through blood, sexual contact and from mother to child during birth. Shared needles, razors and unsterile instruments can transmit it.

How is it not transmitted?

It is not transmitted through shared food, water, hugs or ordinary social contact.

What happens after exposure?

After possible exposure, a clinician checks vaccination status and whether vaccine and/or immunoglobulin are needed. Discuss prevention as soon as possible.

Incubation period

Symptoms can appear approximately 30–180 days after infection. This is not the window period for every laboratory marker.

Window period: when should I test?

Different markers appear at different times. Baseline and repeat testing are planned according to exposure and vaccination; do not wait for symptoms.

What are the symptoms?

Fatigue, nausea, dark urine, abdominal pain and jaundice. These symptoms alone are not enough for a diagnosis.

Can there be no symptoms?

Yes. Chronic infection can go unnoticed for years.

Which parts of the body can be affected?

Mainly the liver. Testing uses blood, not separate throat or rectal swabs.

How is it tested?

The combination of HBsAg, anti-HBs and total anti-HBc distinguishes current infection, immunity and past exposure. Additional tests are ordered when needed.

What sample is needed?

Blood. If infection is identified, HBV DNA, liver blood tests and assessment of the liver may be needed.

What does a positive result mean?

Positive HBsAg suggests current infection; isolated positive anti-HBs may indicate vaccine immunity. Do not interpret one marker without context.

How is it treated?

Acute infection often requires monitoring and supportive care. Antiviral treatment for chronic infection is determined using clinical criteria.

Can I acquire it again?

Recovery often provides immunity. Reactivation is possible during immunosuppression: tell your clinician about previous HBV before such treatment.

What should partners know?

Sexual and household contacts should be referred for testing and vaccination if they lack immunity.

How can I reduce the risk?

Vaccination, condoms and not sharing personal items that may contact blood. Use sterile instruments.

When should I seek medical care?

After a recent significant exposure or for jaundice. Confusion, severe drowsiness and bleeding require emergency care.

What should I do now?

Check your vaccination history and discuss the appropriate marker panel. Arrange medical follow-up for a positive result.

Does a positive antibody mean hepatitis?

Not necessarily. Anti-HBs often indicates protection, while anti-HBc indicates past or current exposure. The combination with HBsAg is essential.

Hepatitis C

Learn more

PrEP: protection you plan in advance

Learn more

HPV

Learn more

What can I do now?

The right test depends on the contact, the sample site and the time since exposure.

Help me choose a test

Testing at CheckPoint

These related services are listed in our current catalogue. This is not a recommendation to take every test: the appropriate method and sample depend on the exposure, symptoms and clinical assessment.

Hepatitis B — specific antibodies (suitable for IVF and before vaccination) (Anti-HBc total; interpretation by a doctor)

Method
Serological testing
Sample
venous blood
Result
3 working days
Price, preparation and conditions

Plan your visit or ask about the right sample

Sources and review

CDC: HBV diagnosis

WHO: hepatitis B

Last updated: 11/09/2026