The essentials at a glance
Mycoplasma genitalium is a sexually transmitted bacterium. It differs from Mycoplasma hominis and Ureaplasma; results for these organisms are not interchangeable.
What is it?
Mycoplasma genitalium is a sexually transmitted bacterium. It differs from Mycoplasma hominis and Ureaplasma; results for these organisms are not interchangeable.
How is it transmitted?
Through sexual contact between mucous membranes. Genital exposure is important; rectal infection is also possible.
How is it not transmitted?
There is no basis for treating ordinary household contact, hugs or shared utensils as transmission routes.
What happens after exposure?
It can cause persistent or recurrent urethritis/cervicitis. Not every broad PCR panel is appropriate for someone without symptoms.
Incubation period
The incubation period is not well established. Giving an exact universal number of days would create misleading certainty.
Window period: when should I test?
There is no universally agreed window for every test and exposure. Testing is ordered according to symptoms and indications, with repetition when needed.
What are the symptoms?
Burning when urinating, urethral discharge, bleeding after sex or cervicitis symptoms. It may contribute to pelvic inflammatory disease.
Can there be no symptoms?
Yes. CDC and European guidance do not recommend routine M. genitalium screening in people without symptoms.
Which parts of the body can be affected?
The urethra and cervix; the rectum can also be affected. Routine throat or rectal screening without clinical indications is not recommended.
How is it tested?
A specific NAAT/PCR for M. genitalium. Resistance testing, where available, supports treatment selection.
What sample is needed?
First-catch urine or an appropriate genital swab, depending on anatomy and the laboratory method.
What does a positive result mean?
Check the exact organism named in the result. A clinician considers M. genitalium alongside symptoms, previous medicines and resistance.
How is it treated?
Sequential treatment guided by resistance is often needed. A single dose of azithromycin on its own is not a reliable approach and can select for resistance.
Can I acquire it again?
Yes. A persistent result can reflect treatment failure or a new exposure; assessment is needed, not automatic repetition of the same antibiotic.
What should partners know?
Current partners should be assessed and tested/treated when indicated. Follow instructions about resuming sex.
How can I reduce the risk?
Condoms and correctly prescribed treatment. Avoiding unnecessary antibiotics also protects future treatment options.
When should I seek medical care?
For recurrent discharge, burning or pelvic pain after previous treatment. Severe pain and fever require prompt assessment.
What should I do now?
Bring previous results and a list of antibiotics you have taken. Ask whether the panel actually includes M. genitalium and whether resistance testing is available.
Are all “mycoplasmas” treated the same way?
No. M. genitalium differs from M. hominis and Ureaplasma. The organism and clinical context matter; a positive broad panel does not automatically mean a prescription is needed.
Chlamydia
Learn more ↗Gonorrhoea
Learn more ↗Trichomoniasis
Learn more ↗What can I do now?
The right test depends on the contact, the sample site and the time since exposure.
Help me choose a test ↗Sexually transmitted infections: what goes unspoken
Read the brochure ↗Testing at CheckPoint
These related services are listed in our current catalogue. This is not a recommendation to take every test: the appropriate method and sample depend on the exposure, symptoms and clinical assessment.
UltraCheck package (syphilis, Candida albicans, Gardnerella vaginalis, herpes simplex virus type 1, herpes simplex virus type 2, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Trichomonas vaginalis, Neisseria gonorrhoeae, Ureaplasma parvum, Ureaplasma urealyticum)
- Method
- Microbiology, virology, PCR
- Sample
- dry swab / sterile container — throat, vaginal, urethral or cervical sample, or urine
- Result
- 3–5 working days
